Agrawal M., Emanuel E., Richards B., et al. “Assessment of Psilocybin Therapy for Patients With Cancer and Major Depression Disorder.” JAMA Oncology, April 2023.

Authors

Manish Agrawal, MD; Ezekiel Emanuel, MD, PhD; Brian Richards, PhD; William Richards, PhD; Kim Roddy, MBA; Paul Thambi, MD

Originally published in JAMA Oncology as Assessment of Psilocybin Therapy for Patients With Cancer and Major Depression Disorder.

This nonrandomized controlled trial used a 1-to-1 therapist-to-patient ratio to administer psilocybin to groups of patients with cancer who were diagnosed with major depression disorder to create a scalable, rapidly effective depression treatment.

About 15% of patients with cancer experience major depression, which is associated with lower treatment adherence and reduced quality of life.^1,2 Yet, oncologists often feel inadequate to address mental health issues, and many treatments have limited success in treating depression.³

Published Date: April 13, 2023